Thalamus

The thalamus is a walnut-sized structure buried at the center of the cerebrum. Nearly all sensory information that enters the cerebral cortex goes through the thalamus. The major exception to this rule... Read more »
Schematic of the organization of the central nervous system, from a sagital view. Henry Gray, Anatomy of the Human Body.

Telencephalon

Telencephalic areas, or cerebrum, arise from the developmental structure known as the telencephalon. These areas include the cerebral cortex, the basal ganglia, and the olfactory bulb. Together with the diencephalon, the telencephalon... Read more »
Depiction of the meninges/membranes of the brain

Meninges

The meninges are made up of three layers (dura mater, arachnoid, and pia mater) that enclose the central nervous system. Working with the cerebrospinal fluid, they function to cushion and nourish the... Read more »

Somatosensory Cortical Areas

VPM and VPL send projections up to primary somatosensory cortex, defined by Brodmann’s areas 3, 1, and 2 sitting on the post-central gyrus. Because all the somatosensory tracts are crossed (remember the... Read more »
Primary terminal nuclei of the afferent (sensory) cranial nerves schematically represented; lateral view. The olfactory and optic centers are not represented. From: Anatomy of the Human Body, Henry Gray.

Trigeminal System

Peripheral Receptors The trigeminal nerve carries information all the same type of peripheral receptors as both the DC-ML and anterolateral systems. Read more »
A typical spinal nerve root showing the dorsal root ganglion ("spinal ganglion" in posterior nerve root in the terminology of Henry Gray).

Anterolateral System

The anterolateral system carries pain and temperature information from the periphery to the VPL nucleus of the thalamus, and on up into the somatosensory cortex. Read more »
The four basic types of touch receptors in glaborous skin.

Dorsal Column – Medial Lemniscus System

Peripheral Receptors Because this system carries a variety of sensations, including light touch, proprioception and vibratory information, it requires a variety of sensory receptor cells. The light touch and vibratory receptors are... Read more »
Conduction velocity varies by fiber type. Unmyelinated, and therefore smallest, C-fibers have the slowest conduction velocity. Progressively more myelinated fibers have higher conduction velocities.

Types of Sensory Fibers

Fibers within a peripheral nerve are classified by conduction speed and diameter. Read more »

Drug Therapy for Alzheimer’s Dementia

Alzheimer’s dementia (AD) is the most common cause of dementia in western society.  Disease specific treatments that are currently available do not appear to alter the course of the illness, though may... Read more »

Neurosyphilis

Syphilis, a sexually transmitted infection caused by the spirochete Treponema pallidum has recently been re-emerging in the general population. Central nervous system involvement by this infection is referred to as neurosyphilis.  Neurosyphilis... Read more »