multiple sclerosis - DocNeuro

Tumefactive multiple sclerosis

Christopher Buckle MD — Sat, 07 Dec 2013 19:55:18 +0000

Tumefactive multiple sclerosis (MS) is an unusual but important manifestation of multiple sclerosis. This is a patient with tumefactive MS. Notice the incomplete rim enhancement around the right frontal mass on the T1 post contrast sequence. This incomplete rim enhancement is classic for a tumefactive demyelinating lesion as opposed to a neoplasm. A. T1 precontrast and […]

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Dr. Anthony Reder – advice for the resident and MS fellow

Rui Guan MD — Mon, 16 Sep 2013 21:15:48 +0000

Dr. Rui Guan interviews Dr. Anthony Reder, an MS specialist at the University of Chicago. This article, geared to residents and fellows, gives insight into Dr. Reder’s world. About Dr. Reder: Dr. Reder directs the Neurology and Inflammatory Disease Infusion Center at the University of Chicago and is an expert in multiple sclerosis, having written over a […]

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Chat with MS practice expert – Dr. Anthony Reder

Rui Guan MD — Mon, 16 Sep 2013 21:00:05 +0000

Multiple Sclerosis expert Dr. Anthony Reder from the University of Chicago Department of neurology is interviewed by Dr. Rui Guan on topics in MS of interest to neurologists and general practitioners alike. About Dr. Anthony Reder: Dr. Reder has authored or co-authored over 100 scientific papers on multiple sclerosis, ranging from the basic science of […]

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Expanded disability status score for MS

Rui Guan MD — Sat, 07 Sep 2013 14:59:14 +0000

Disability progression is assessed by the Expanded Disability Status Score (EDSS). To make sense of the scale from 0 (normal neuro exam) to 10 (death due to MS), a few pointers: 1-1.5 is no disability that the patient notes, e.g. decreased vibration sense or red desaturation 3-3.5, billed as “disability is mild to moderate,” but […]

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Uthoff’s phenomenon

Rui Guan MD — Sat, 07 Sep 2013 13:51:31 +0000

Uhthoff’s phenomenon describes the worsening of multiple sclerosis symptoms with overheating, e.g. exercise, hot weather, or saunas, which cause conduction delay or block in a demyelinated nerves. In practice, even a change in ambient body temperature by 0.5 degree can increase prior symptoms.

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MS update – September 2013

Rui Guan MD — Fri, 06 Sep 2013 15:26:39 +0000

“Multiple sclerosis (MS) does not really remit” was the opening theme of this weekend’s conference. Lead by three MS-experts, Drs. Omar Khan, Guy Buckle, and Stephen Krieger, a roomful of neurology residents reviewed the epidemiology, classification, immunopathogenesis, disease course and their impact on therapeutic advancement. MS does not remit – insights from pathology As MS […]

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Optic Neuritis

Jeffrey Waggoner MD — Fri, 15 Mar 2013 22:00:59 +0000

Optic neuritis is inflammation of the optic nerve. It is principally due to demyelinization and is closely associated with multiple sclerosis (MS). Potential etiologies of optic neuritis Almost one fifth of new cases of MS present as an optic neuritis. Studies estimate that 40% to 50% of MS patients will eventually develop an optic neuritis. […]

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Multiple Sclerosis

Rui Guan MD — Fri, 15 Mar 2013 20:48:28 +0000

MULTIPLE SCLEROSIS is aptly named for the scleroses (scars or plaques) that occur as the disease resurfaces in multiple episodes. Diagnosis of multiple sclerosis – the 2010 update The McDonald Criteria for diagnosing MS was updated in 2010 to help simplify the use of images, and in cases, use one MRI to establish dissemination in space and time […]

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Dawson’s Fingers

Christopher Buckle MD — Thu, 23 Aug 2012 04:15:46 +0000

Multiple sclerosis is the most common demyelinaing disease and the most common disabling CNS disease of young adults. The etiology is not certain but likely autoimmune. The disease is characterized by the dissemination of T2 hyperintense white matter plaques across space and time. Extension of these plaques along perimedullary veins perpendicular to the callosum, also […]

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