Neurodevelopmental Disorders - DocNeuro

Schizencephaly

Naoum P. Issa MD PhD — Fri, 08 Aug 2014 02:06:51 +0000

Schizencephaly is a developmental abnormality in brain structure consisting of a cleft from the pia into brain parenchyma, lined by heterotopic gray matter. Clefts that connect with the lateral ventricle are “open lip” schizencephaly and clefts that do not connect with the ventricle (like that shown in the image above) are closed lip. The […]

The post Schizencephaly first appeared on DocNeuro.

The post Schizencephaly appeared first on DocNeuro.

Cobalamin Deficiency

Naoum P. Issa MD PhD — Fri, 15 Mar 2013 22:10:48 +0000

Vitamin B12, also known as cobalamin, plays an important role in a number of physiological functions, Its deficiency has been associated with macrocytic anemia and number of neuropsychiatric disorders. Further, at the present time, B12 deficiency is being explored with relation to hyperhomocysteinemia and promotion of atherosclerosis. Measurement of serum vitamin B12 levels is now […]

The post Cobalamin Deficiency first appeared on DocNeuro.

The post Cobalamin Deficiency appeared first on DocNeuro.

Wilson’s Disease

Jeffrey Waggoner MD — Fri, 15 Mar 2013 19:13:23 +0000

Wilson disease is an autosomal recessive disorder of copper metabolism. Patients with the disease experience excessive deposition of copper in the liver, brain, and other tissues. It appears that the primary defect is excessive absorption of copper from the small intestine and decreased excretion of copper by the liver. The processes of incorporation of copper […]

The post Wilson’s Disease first appeared on DocNeuro.

The post Wilson’s Disease appeared first on DocNeuro.

Pineal Cyst

Christopher Buckle MD — Thu, 21 Feb 2013 00:48:12 +0000

The pineal gland is a small (6-8 mm) midline endocrine structure, partly responsible for the production of serotonin , a neurotransmitter responsible for the modulation of “mood”, expressed by its effect on such fundamental behaviors as appetite, sleep, sex and mood. Diagnosis: Pineal Cyst Figure 1: (a,red arrow) axial FLAIR demonstrates a mildly hyperintense pineal […]

The post Pineal Cyst first appeared on DocNeuro.

The post Pineal Cyst appeared first on DocNeuro.

Germinoma

Christopher Buckle MD — Thu, 21 Feb 2013 00:42:45 +0000

Tumors of the pineal gland can be categorized into pineal cell and germ cell depending of their cell type of origin. Germ cell tumors (GCT’s) are more common than pineal cell tumors. The two most GCT’s are germinoma and teratoma. . Diagnosis: Germinoma Figure 1: Pineal mass with heterogenous T1 (a, red arrow) and T2 […]

The post Germinoma first appeared on DocNeuro.

The post Germinoma appeared first on DocNeuro.

Chiari Malformation

Christopher Buckle MD — Sun, 25 Nov 2012 17:22:54 +0000

Arnold Chiari 1 malformation is a congenital anomaly of the brain parenchyma characterized by descent of the cerebellar tonsils below the foramen magnum due to a mismatch between the size of the posterior fossa and the cerebellum. Chari 1 malformation differs from the milder tonsillar ectopia (low lying cerebellar tonsils that do not meet criteria […]

The post Chiari Malformation first appeared on DocNeuro.

The post Chiari Malformation appeared first on DocNeuro.

Corpus Callosum Agenesis

Naoum P. Issa MD PhD — Sat, 22 Sep 2012 17:22:29 +0000

In this case, images show a congenital malformation in which the corpus callosum, which connects the left and right cerebral hemispheres, failed to develop. While this abnormality is rare, there are many potential causes: in this case it was associated with a chromasomal duplication. The corpus callosum develops between the 21st and 84th day of […]

The post Corpus Callosum Agenesis first appeared on DocNeuro.

The post Corpus Callosum Agenesis appeared first on DocNeuro.