Cefepime Neurotoxicity

Cefepime is a cephalosporin antibiotic typically used when broad spectrum coverage including Pseudomonas aerigonsa is needed. However, it can produce cefepime neurotoxicity with encephalopathy, myoclonus, reversible aphasia, and/or convulsive or subclinical seizures. Read more »

Juvenile Myoclonic Epilepsy

Juvenile myoclonic epilepsy (JME) is one of the most common generalized epilepsy syndromes and typically presents in the teen years. Like absence epilepsy, it is considered a primary generalized epilepsy, rather than... Read more »

Absence Epilepsy

Absence epilepsy is a type of primary generalized epilepsy in children, and usually presents as staring spells. Read more »

Carnitine palmitoyltransferase (CPT) deficiency

Carnitine palmitoyltransferase II (CPT) deficiency is the most common inherited lipid-metabolism disorder in skeletal muscle. Read more »
McArdle disease, H&E and PAS stain

McArdle Disease

McArdle disease is a glycogen storage disease in which the enzyme muscle myophosphorylase is deficient. It is commonly known as glycogen storage disease V. Read more »
Mitochondrial myopathy seen on H&E stain, trichrome stain, CO stain

Mitochondrial myopathy

Mitochondrial myopathy can be caused by metabolic abnormalities related to mutations in the mitochondrial genome or mutations in the somatic genome that produce abnormal mitochondrial proteins. Read more »
Cerebral white matter tracts by diffusion tensor imaging. Licensed under Creative Commons Attribution-Share Alike 3.0 via Wikimedia Commons

Conductive aphasia

Conductive aphasia is defined as the inability to repeat a spoken phrase, even when comprehension is intact and speech production is otherwise normal. Read more »
expressive aphasia classification

Expressive aphasia

Patients with expressive aphasia have difficultly speaking fluently, although they can understand what other people say when they are spoken to. Read more »
receptive aphasia classification

Receptive aphasia

Patients with receptive aphasia can speak clearly (fluently) but cannot understand what others say and have difficulty putting together meaningful sentences. Read more »
types of aphasia

Classifying aphasia

Aphasia is defined as a loss of the ability to understand or produce speech, usually caused by damage to the cerebrum. It is important to clinically classify the type of aphasia a... Read more »