{"id":78,"date":"2013-02-16T22:56:24","date_gmt":"2013-02-16T22:56:24","guid":{"rendered":"https:\/\/docneuro.jz7sunfr-liquidwebsites.com\/neurofibromatosis\/"},"modified":"2013-02-16T22:56:24","modified_gmt":"2013-02-16T22:56:24","slug":"neurofibromatosis","status":"publish","type":"post","link":"https:\/\/docneuro.com\/neurofibromatosis\/","title":{"rendered":"Neurofibromatosis"},"content":{"rendered":"<p>Also known as Von Recklinghausen\u2019s disease, neurofibromatosis (NF) is an inherited neurocutaneous syndrome with systemic manifestations, the most notable of which is the occurrence of multiple neurofibromas.<\/p>\n<p>  <!--more-->  <\/p>\n<h2>Diagnosis: Neurofibromatosis<\/h2>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\" size-full wp-image-384\" src=\"https:\/\/docneuro.com\/wp-content\/uploads\/2013\/02\/neurofibromatosis_ab_marked.jpg\" border=\"0\" style=\"border: 0;\" width=\"600\" height=\"334\" srcset=\"https:\/\/docneuro.com\/wp-content\/uploads\/2013\/02\/neurofibromatosis_ab_marked.jpg 600w, https:\/\/docneuro.com\/wp-content\/uploads\/2013\/02\/neurofibromatosis_ab_marked-300x167.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p> <center> <\/p>\n<p><img decoding=\"async\" class=\" size-full wp-image-385\" src=\"https:\/\/docneuro.com\/wp-content\/uploads\/2013\/02\/neurofibromatosis_c_marked.jpg\" border=\"0\" style=\"border: 0;\" width=\"400\" height=\"445\" srcset=\"https:\/\/docneuro.com\/wp-content\/uploads\/2013\/02\/neurofibromatosis_c_marked.jpg 400w, https:\/\/docneuro.com\/wp-content\/uploads\/2013\/02\/neurofibromatosis_c_marked-270x300.jpg 270w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><\/p>\n<p> <\/center> <\/p>\n<p><strong>Figure 1: <\/strong>(a, red arrow) axial T1, (b, blue arrow) T1 post contrast and (c, green arrow) T2 with fat suppression demonstrate multiple T2 hyperintense, homogenously enhancing ovoid and dumbbell shaped masses, many in contiguity with the neural-foramina, most consistent with neurofibromatosis.<\/p>\n<p>Two types of NF are recognized and they have different manifestations in the central and peripheral nervous system. Type 1 NF is characterized clinically by the presence of caf\u00e9 au lait spots. Neural manifestations include the presence of plexiform (multiple, confluent) neurofibromas, macrocephaly, dysplasia of the sphenoid wing, optic nerve gliomas, poorly defined lesions of the white matter that lack mass effect, and vascular anomalies, specifically intimal hyperplasia leading to intracranial stenosis and aneurysms.<\/p>\n<p>Neurofibromatosis type 2, on the other hand is characterized by the presence of multiple meningiomas, schwannomas, and ependymoma\u2019s. NF 2 also has a pathognomonic finding \u2013 bilateral vestibular schwannomas .Cranial nerves 3,5 and 12 are other less common sites for schwannomas in NF 2. NF 2 is less common, with an incidence of about 1:25,000.It usually presents with hearing loss and vertigo in patient\u2019s aged 20-40.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Also known as Von Recklinghausen\u2019s disease, neurofibromatosis (NF) is an inherited neurocutaneous syndrome with systemic manifestations, the most notable of which is the occurrence of multiple neurofibromas.<\/p>\n","protected":false},"author":3,"featured_media":384,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[17],"tags":[31,210,208,209],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Neurofibromatosis - DocNeuro<\/title>\n<meta name=\"description\" content=\"A case presentation of a child with neurofibromatosis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/docneuro.com\/neurofibromatosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neurofibromatosis - 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