MRI - DocNeuro

MSA hot cross buns sign

Naoum P. Issa MD PhD — Tue, 29 Jul 2014 17:12:41 +0000

Multi-systems atrophy is a progressive neurodegenerative disorder often initially difficult to differentiate from Parkinson’s Disease. Patients present with autonomic instability (fainting due to orthostasis, fluctuating heart rate, urinary incontinence or difficulty emptying bladder) and movement disorders (tremor, rigidity, ataxia). MSA is further classified into cerebellar predominant (MSA-C) or Parkinsonian predominant (MSA-P) depending on the primary […]

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Tumefactive multiple sclerosis

Christopher Buckle MD — Sat, 07 Dec 2013 19:55:18 +0000

Tumefactive multiple sclerosis (MS) is an unusual but important manifestation of multiple sclerosis. This is a patient with tumefactive MS. Notice the incomplete rim enhancement around the right frontal mass on the T1 post contrast sequence. This incomplete rim enhancement is classic for a tumefactive demyelinating lesion as opposed to a neoplasm. A. T1 precontrast and […]

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Functional MRI

Christopher Buckle MD — Thu, 21 Feb 2013 18:06:20 +0000

Functional MRI (fMRI) is a new imaging modality that allows for dynamic evaluation of brain function in addition to structure. In the brain, blood flow is tightly coupled to neuron function. Neurons depend on local blood supply for glucose, so when neurons fire, the local blood flow is increased to provide the glucose necessary for […]

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Neurofibromatosis

Christopher Buckle MD — Sat, 16 Feb 2013 22:56:24 +0000

Also known as Von Recklinghausen’s disease, neurofibromatosis (NF) is an inherited neurocutaneous syndrome with systemic manifestations, the most notable of which is the occurrence of multiple neurofibromas. Diagnosis: Neurofibromatosis Figure 1: (a, red arrow) axial T1, (b, blue arrow) T1 post contrast and (c, green arrow) T2 with fat suppression demonstrate multiple T2 hyperintense, homogenously […]

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Astrocytoma

Christopher Buckle MD — Sat, 16 Feb 2013 22:55:14 +0000

Neoplasms of the astrocytes (astrocytomas), are the most common form of primary brain neoplasm. The prognosis for astrocytomas depends on their grade and is better for low grade than high grade neoplasms. Diagnosis: Low grade astrocytoma Figure 1: axial FLAIR (a, red arrow), DWI (b, blue arrow) and T1 post contrast (c ,green arrow) images […]

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Herpes Encephalitis

Christopher Buckle MD — Sat, 16 Feb 2013 22:46:23 +0000

Herpes simplex virus type 1 (HSV-1) is a prevalent virus with an affinity for the nervous system. Reactivation of the virus within the brain parenchyma either directly or through retrograde spread along the cranial nerves (especially trigeminal and olfactory) can result in a severe encephalitis that is universally fatal without early treatment. In fact, HSV […]

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Brain MRI Spectroscopy

Naoum P. Issa MD PhD — Tue, 29 May 2012 20:37:10 +0000

What is brain MR spectroscopy used for? MR spectroscopy gives a chemical profile of a region of brain. This is useful in differentiating normal brain tissue from tumor, regions with ischemia, or other tissue abnormalities. Abnormal areas identified on structural MRI are typically compared to the normal contralateral area as a control. A summary of […]

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