{"id":39,"date":"2012-09-28T18:53:54","date_gmt":"2012-09-28T18:53:54","guid":{"rendered":"https:\/\/docneuro.jz7sunfr-liquidwebsites.com\/hypothalamic-hemartoma-gelastic-seizures\/"},"modified":"2019-12-30T22:18:25","modified_gmt":"2019-12-30T22:18:25","slug":"hypothalamic-hemartoma-gelastic-seizures","status":"publish","type":"post","link":"https:\/\/docneuro.com\/hypothalamic-hemartoma-gelastic-seizures\/","title":{"rendered":"Hypothalamic Hemartoma and Gelastic Seizures"},"content":{"rendered":"<p>The MR images show an abnormal growth hanging down from the hypothalamus. This is a hypothalamic hemartoma, which in some cases can be a type of <a href=\"https:\/\/docneuro.com\/band-heterotopia\/\" target=\"_blank\" title=\"Band Heterotopia\" rel=\"noopener noreferrer\">grey matter heterotopia<\/a>\u00a0within the tuber cinereum. It is usually a non-neoplastic congenital abnormality that can result in stereotypical seizures and behaviors.<\/p>\n<p>  <!--more-->  <\/p>\n<p><img decoding=\"async\" class=\" size-full wp-image-365\" src=\"https:\/\/docneuro.com\/wp-content\/uploads\/2012\/09\/hypothalamic-hemartoma.PNG\" border=\"0\" alt=\"\" title=\"hypothalamic hemartoma - AKA tuber cinereum hamartoma\" width=\"600\" srcset=\"https:\/\/docneuro.com\/wp-content\/uploads\/2012\/09\/hypothalamic-hemartoma.PNG 808w, https:\/\/docneuro.com\/wp-content\/uploads\/2012\/09\/hypothalamic-hemartoma-300x182.png 300w, https:\/\/docneuro.com\/wp-content\/uploads\/2012\/09\/hypothalamic-hemartoma-768x465.png 768w\" sizes=\"(max-width: 808px) 100vw, 808px\" \/><\/p>\n<p>The classic clinical picture is of a male (slightly more frequent than in females) with precocious puberty and fits of uncontrolled energy accompanied by either laughter or crying &#8211; the so-called gelastic seizures. A gelastic seizure can often be followed by other types of seizures including atonic (drop-seizures), simple partial, or complex partial seizures. Gelastic seizures are difficult to control completely with anti-epileptic drugs but the medications used for partial complex epilepsy can often reduce seizure frequency.<\/p>\n<p>About half the cases of hypothalamic hemartoma are associated with Pallister-Hall Syndrome. Pallister-Hall results from an autosomal dominant mutation of the gene-regulator GL13. In addition to hypothalamic hemartoma, children with Pallister-Hall can have polydactyly, cutaneous syndactyly, bifid epiglottis, kidney abnormalities and an imperforate anus.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The MR images show an abnormal growth hanging down from the hypothalamus. This is a hypothalamic hemartoma, which in some cases can be a type of grey matter heterotopia\u00a0within the tuber cinereum. It is usually a non-neoplastic congenital abnormality that can result in stereotypical seizures and behaviors.<\/p>\n","protected":false},"author":2,"featured_media":365,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[14],"tags":[119,118,120,117,121],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hypothalamic Hemartoma and Gelastic Seizures - DocNeuro<\/title>\n<meta name=\"description\" content=\"Clinical presentation of gelastic seizures in the context of a hypothalamic hemartoma.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/docneuro.com\/hypothalamic-hemartoma-gelastic-seizures\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hypothalamic Hemartoma and Gelastic Seizures - DocNeuro\" \/>\n<meta property=\"og:description\" content=\"Clinical presentation of gelastic seizures in the context of a hypothalamic hemartoma.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/docneuro.com\/hypothalamic-hemartoma-gelastic-seizures\/\" \/>\n<meta property=\"og:site_name\" content=\"DocNeuro\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/DocNeuro\/\" \/>\n<meta property=\"article:published_time\" content=\"2012-09-28T18:53:54+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-12-30T22:18:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/docneuro.com\/wp-content\/uploads\/2012\/09\/hypothalamic-hemartoma.PNG\" \/>\n\t<meta property=\"og:image:width\" content=\"808\" \/>\n\t<meta property=\"og:image:height\" content=\"489\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Naoum P. Issa MD PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@DocNeuroCom\" \/>\n<meta name=\"twitter:site\" content=\"@DocNeuroCom\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Naoum P. 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